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Perineural Injection Therapy

Perineural Injection Therapy, or neural prolotherapy, is a simple solution in the treatment of inflamed and injured nerves. It involves the subcutaneous injection of pharmaceutical-grade dextrose to safely and effectively heal injured nerves and restore tissue function.

Perineural Injection Therapy may be helpful for:

  • Chronic headaches and migraines

  • Chronic pain throughout the body

  • Low back pain

  • Neck pain

  • Post surgical pain

  • Overuse pain

How Does it Work?

Nerves are commonly injured at sites on the body that pass over bony edges or through various levels of connective tissue called fascia. In addition, stretching or crushing of nerves may also lead to injury. In the normal state, the TRPV1 receptor helps maintain normal healthy tissue. When injured, nerves turn up the volume of these receptors leading to localized inflammation, pain, and eventually degeneration. Ongoing research shows that dextrose may bind to this TRPV1 receptor leading to restoration of healthy nerves and tissue.

Solution: Buffered 5% dextrose

Injection site: Multiple small, shallow, injections under the skin along the cutaneous nerve path.

Frequency: Usually 1-2 weeks apart.

Treatments required: Treatment time is individualized but generally 4-6 treatments are needed.

Downtime: None